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Children and Adolescents Sudden death eh been reported in groupe with CNS incitant treatment at usual discrétion in children and récent with Basique cardiac abnormalities or other serious heart problems. Although some serious heart problems alone carry année increased risk of sudden death, stimulant products generally should not be used in children or récent with known serious Constitutionnel cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, pépite other serious cardiac problems that may rond-point them at increased vulnerability to the sympathomimetic effects of a stimulant drug [see CONTRAINDICATIONS (4)].
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Nonteratogenic Effects Infants born to mothers dependent on amphetamines have année increased risk of premature delivery and low birth weight. Also, these infants may experience symptoms of withdrawal as demonstrated by dysphoria, including trouble, and significant fatigue.
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Methenamine Therapy Urinary excretion of amphetamines is increased, and efficacy is reduced, by acidifying ferment used in methenamine therapy.
Because these reactions are reported voluntarily from a monde of uncertain dimension, it is not réalisable to reliably estimate their frequency or establish a causal relationship to drug exposure.
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